Protracted diarrhoea in infancy.

Protracted diarrhoea in infancy.

Protracted diarrhoea in infancy

1 of 2 categories according to whether a specific diagnosis was established or not. A diagnosis (category 1) was established in 59 (72 %), the commonest diagnoses being coeliac disease (33 2 %), secondary disaccharide intolerance (12 2%), and cows' milk protein intolerance (11 3 %). Other diagnoses included primary sucrase-isomaltase deficiency, Shwachman's syndrome, ulcerative colitis, ganglio...

A family study of protracted diarrhoea in infancy.

A family study of undiagnosed protracted diarrhoea in infancy was undertaken, based on 67 such patients, seen at The Hospital for Sick Children, London, over a 6-year period. All were fully investigated with the exclusion of those with known cause, such as coeliac disease, cow's milk intolerance, or enteric infections. The families were traced and visited. The material is certainly heterogeneou...

Human milk in the management of protracted diarrhoea of infancy.

Eleven of 13 children with the protracted diarrhoea syndrome of infancy were successfully treated with human milk. All the infants, who were severely malnourished, had deteriorated while fed on a wide range of highly modified formulas. Seven infants responded promptly with cessation of weight loss and diarrhoea; in four others, human milk was used to re-establish oral nutrition after a period o...

Lethal familial protracted diarrhoea.

24 children with severe protracted diarrhoea from 10 families, in which at least one sibling was affected, are reported. In two families the siblings were from 1st-cousin marriages, in one family both parents had unaffected children from previous marriages, and in another family the mother had a normal daughter from an earlier marriage. The onset of the diarrhoea was on the first day of life in...